Transformable protein–gold hybrid materials serve as supramolecular vehicles for gene delivery
نویسندگان
چکیده
منابع مشابه
Mesenchymal Stem Cells as Gene Delivery Vehicles
Mesenchymal stem cells (MSCs) possess a battery of unique properties which make them ideally suited not only for cellular therapies/regenerative medicine, but also as vehicles for gene delivery in a wide array of clinical settings. These include: 1) widespread distribution throughout the body; 2) ease of isolation and ability to be extensively expanded in culture without loss of potential; 3) t...
متن کاملPrions on the run: How extracellular vesicles serve as delivery vehicles for self-templating protein aggregates
Extracellular vesicles (EVs) are actively secreted, membrane-bound communication vehicles that exchange biomolecules between cells. EVs also serve as dissemination vehicles for pathogens, including prions, proteinaceous infectious agents that cause transmissible spongiform encephalopathies (TSEs) in mammals. Increasing evidence accumulates that diverse protein aggregates associated with common ...
متن کاملPolymer-functionalized nanodiamond platforms as vehicles for gene delivery.
Gene therapy holds great promise for treating diseases ranging from inherited disorders to acquired conditions and cancers. Nonetheless, because a method of gene delivery that is both effective and safe has remained elusive, these successes were limited. Functional nanodiamonds (NDs) are rapidly emerging as promising carriers for next-generation therapeutics with demonstrated potential. Here we...
متن کاملTransformable periodic mesoporous organosilica materials.
The synthesis of novel periodic mesoporous organosilica (PMO) materials incorporating a mixture of functional monomers (cis- and trans-stilbene-based) and structural monomers has been accomplished. EDX analysis of these materials in combination with HAADF imaging of OsO(4)-stained samples reveals a homogeneous distribution of trans-olefin within the co-condensed aromatic organosilica matrix. Oz...
متن کاملLipoidal Soft Hybrid Biocarriers of Supramolecular Construction for Drug Delivery
Lipid-based innovations have achieved new heights during the last few years as an essential component of drug development. The current challenge of drug delivery is liberation of drug agents at the right time in a safe and reproducible manner to a specific target site. A number of novel drug delivery systems has emerged encompassing various routes of administration, to achieve controlled and ta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: RSC Advances
سال: 2017
ISSN: 2046-2069
DOI: 10.1039/c7ra10141d